Drug Response Test (PGx)

We offer comprehensive pharmacogenomic tests covering hundreds of the most commonly prescribed drugs across a large cross section of therapeutic areas. Pharmacogenomic testing results can reduce adverse drug reaction, help optimize dosing, and assist in selecting the most effective medication.

Drug Response Test (PGx)

Characteristics

  • Risk assessment of altered drug metabolism based on genotype
  • Report customization according to specialty
  • Reports only include selections of variant / drug relationships for which there is strong evidence of drug response being affected by a patient’ s genotype

(This test only reports variant/drug relationships that have Clinical Pharmacogenetics Implementation Consortium (CPIC) evidence level of A or B, a PharmGKB evidence level of 1 or 2, or are referenced in the FDA drug label.)

Targeted Therapeutic Areas

  Therapeutic Areas Drugs
Cardiovascular ACE Inhibitors, Antiarrhythmic, Anticoagulant, Antiplatelets Beta Blockers, Diuretics, Statins
Endocrinology Antithyroid, Sulfonylureas Thiazolidnediones
Infectious Disease Antibiotics, Antifungal Antimalarials, Antivirals
Gastroenterology Laxatives Proton Pump Inhibitors (PPIs)
Neurology Anticonvulsant, Central ACH Inhibitors Central Monoamine-Depleting Agents
Oncology 5-HT3 Antagonists, Platinum Analogs, Purine Analogs, Pyrimidine Analogs Topoisomerase Inhibitors, Tyrosine Kinase Inhibitors, Others
Pain Management Nonsteroidal Anti-inflammatory Drugs (NSAIDS), Opioids Others
Psychiatry Antipsychotics, Benzodiazepines, Selective Serotonin Reuptake Inhibitors Serotonin-Norepinephrine Reuptake Inhibitors, Tricyclic Antidepressants, Others
Other Drugs Genetic Disease, Gynecology, Immunology, Ophthalmology Toxicology, Urology, Other Indications

Targeted Genes (59 genes)

ABCB1 / ABCG2 / ADD1 / ANKK1 / APOE / CBR3 / CES1 / CFTR / COMT / CYP2B6 / CYP2C19 / CYP2C8 / CYP2C9 / CYP2D6 / CYP3A4 / CYP3A5 / CYP4F2 / DPYD / DRD2 / EPHX1 / ERCC1 / F2 / F5 / FASTKD3, M-TRR / G6PD / GSTP1 / HAS3 / HLA-A / HLA-B / HLA-C / HLA-DPB1 / HLA-DQA1 / HLA-DRB1 / HTR1A / ITPA / KIF6 / LTC4S / MTHFR / NAT2 / NQO1 / NUDT15 / OPRM1 / PTGS1 / PTPGFR / SLC28A3 / SLC6A4 / SLCO1B1 / TNF / TP53 / TPMT / TYMS / UGT1A1 / UGT1A4 / UGT2B15 / UMPS / VDR / VKORC1 / XPC / XRCC1

Example Report

Please see following PDF file for the example report.

PDF Download

Service Flow

  • Inquiry

    Please fill in the following quotation request form on our website.
  • Quotation

    You will receive a quotation based on the information provided in your request. The purchase order will be sent to you after we have confirmed your agreement on the quotation.
  • Sample Collection

    Please send the DNA samples after you have placed an order. We will send the receipt after receiving your samples.
  • Analysis

    The DNA sample we receive will be run, using next generation sequencing. Extracted Data will be analyzed using Phosphorus’s proprietary bioinformatics software, ‘Elements’.
  • Reporting

    All components interpreted as variants are vetted through a rigorous quality control process that includes internal validations by Ph.D. scientists. You will receive the final patient reports via e-mail.

*Please note that this test is intended for research purposes only.

Quotation Request Form

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Preferred Service
*All therapeutic area is included in “MD-PGX-001 Drug Response Test (PGx)”. Please select “MD-PGX-002 Drug Response Test Customized Report” if you prefer to narrow down the specific therapeutic area.
    • Customized Report
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